Historical QOD 1/15/09: Describe the potential long-term effects related to significant carbon monoxide exposure.
Patients with significant exposure to carbon monoxide may be at risk for delayed neurologic sequelae including cognitive impairment, dementia, amnesia, psychosis, paralysis, cortical blindness, and peripheral neuropathy, Parkinsonism, and chorea. In addition, a recent prospective cohort study also reported an association between carbon monoxide exposure and increased mortality in patients with myocardial injury (troponin I =0.7 ng/ml or CK-MB =5.0 ng/ml) at the time of exposure.
Henry CR. Satran D. Lindgren B. Adkinson C. Nicholson CI. Henry TD. Myocardial injury and long-term mortality following moderate to severe carbon monoxide poisoning. JAMA. 295(4):398-402, 2006 Jan 25.
Contributed by: M Greenberg