A cross-sectional study of patients admitted with tramadol poisoning conducted at a tertiary referral hospital in Tehran, Iran compared genetic polymorphisms of mu opioid receptors and adverse effects of tramadol overdose. What was the relationship between mu1 A118G genotype and adverse effects of tramadol?
This study found no significant association between the opioid receptor mu1 A118G polymorphism and adverse outcomes in tramadol-poisoned patients
Ershad, A., Shafiee Dolat Abadi, S., Ebrahimian, M., Hadeiy, S. K., Zamani, N., Kolahi, A. A., … Hassanian-Moghaddam, H. (2024). Association of the OPRM1 variant rs1799971 (A118G) and clinical manifestations in tramadol poisoned patients: a cross-sectional study. Clinical Toxicology, 62(6), 357–363. https://doi.org/10.1080/15563650.2024.2366921
Contributed by Kristine Nanagas, MD