Question of the Day – Friday, February 17, 2023
How much oxygen is liberated from 1 mL of 30% hydrogen peroxide? “1 mL of 35% (v/v) hydrogen peroxide releases 100 mL oxygen” Mullins ME, Beltran JT. Acute cerebral gas embolism from hydrogen peroxide ingestion successfully treated with hyperbaric oxygen. J Toxicol Clin Toxicol. 1998;36(3):253-6….
Question of the Day – Thursday, February 16, 2023
Historical QOD 11/11/08: What ear malformations are typically seen in children whose mothers took isotretinoin during pregnancy? Partial duplications and tissue reductions and displacements Hall BK. Summarizing craniofacial genetics and developmental biology (SCGDB). Am J Med Genet A. 2014 Apr;164A(4):884-91. doi: 10.1002/ajmg.a.35288. Epub 2014 Jan…
Question of the Day – Wednesday, February 15, 2023
What simple technique can be employed to differentiate the composition of an unidentified mothball (camphor vs naphthalene vs paradichlorobenzene)? Each substance has a distinct specific gravity, allowing mothballs to be differentiated based on buoyancy (camphor=0.992, naphthalene=1.15, paradichlorobenzene=1.30). Camphor-containing mothballs will float in water while both…
Question of the Day – Tuesday, February 14, 2023
In a recent metanalysis of studies examining whether the paracetamol x transferase multiplication product predicted hepatotoxicity after paracetamol overdose, the authors analyzed 5,036 participants as an entire group and as subgroups. This product was particularly helpful in ruling out hepatotoxicity in which presentation: single acute…
Question of the Day – Monday, February 13, 2023
What is a proposed mechanism of cyclosporine as a potential treatment for amatoxin-poisoned patients? MacKenzie CA et al. reported a small case series of cyclosporine as a novel treatment for amatoxin containing mushroom poisonings. Cyclosporine, in vitro, completely inhibited OATP1B3-mediated cellular uptake of alpha-amanitin. MacKenzie…
Question of the Day – Friday, February 10, 2023
This element (atomic number 20) is frequently used as a PVC stabilizer, pigment, neutron absorber in power plants, component of battery manufacturing, and anticorrosive agent. It can lead to a terrible pneumonitis, forms a complex with metallothionein and ultimately ends up filtered by the glomerulus…
Question of the Day – Thursday, February 9, 2023
Historical QOD 11/10/08: What is the most characteristic radiological finding in fetal warfarin syndrome? Epiphyseal stippling Sathienkijkanchai A, Wasant P. Fetal warfarin syndrome. J Med Assoc Thai. 2005 Nov;88 Suppl 8:S246-50. PMID: 16856447.
Question of the Day – Wednesday, February 8, 2023
A young man ingests a rodenticide and presents with emesis, acute liver failure, and radiopaque debris seen on an abdominal radiograph shown. He progresses to develop cardiac arrest. What is a potential causative agent explaining the presentation? Zinc phosphide. While rarely used as a rodenticide…
Question of the Day – Tuesday, February 7, 2023
What drug of abuse was intercepted from body packers with intent into smuggling into Qatar for the FIFA 2022 World Cup event? Almost 2.6 kg of hashish were retrieved from two body packers, who intended to sell the drug during the tournament. Hossein Hassanian-Moghaddam, Babak…
Question of the Day – Monday, February 6, 2023
A person moves 1 meter to 2 meters from an unshielded Cesium-137 source made of cesium chloride. What percent reduction of radiation exposure will the person experience? A 50.0% B 75.0% C 87.5% D 88.9% Correct answer B. The dose of radiation received…