Question Of The Day

The below image demonstrates a classic finding associated which deficiency? Angular Chelitis and tongue erosions associated with Zinc Deficiency in a patient with acquired acrodermatitis enteropathica. Other findings consistent with this diagnosis include alopecia, blepharitis, diarrheal illness, nail dystrophy, and Scaly, pink plaques over extremities,…

Historical QOD 11/26/08: Which of the following findings suggests heroin use rather than codeine use? A. Serum morphine:serum codeine <1 B. Serum morphine:serum codeine > 1 C. Urine morphine:urine codeine <1 D. Urine morphine:urine codeine > 1 E. Negative 6 acetylmorphine (6-AM) in the urine…

The following image reveals perifollicular hemorrhage with corkscrew hairs. These findings are consistent with which disease process? The above image depicts clinical findings consistent with Vitamin C deficiency (Scurvy). Additional clinical findings may include petechciae, palpable purpura, ecchymosis, gingivitis, fatigue, myalgia, arthralgias and poor wound…

What is the rate of death from non-fire related carbon monoxide poisoning per 1 million in the United States annually? According to the cited source, which reviewed 4 data sets (Poison Control Centers, emergency department visits, hospital discharges, and death certificates), the rate of non-fire…

A recent prospective study of patients suffering Carbon Monoxide toxicity found an association between corticosteroid threatment and a lower incidence of Delayed Neurological Sequelae. What was the dosing regimen used in this study? The investigators used 10 mg intravenous dexamethasone every 24 hours for 3…

In a single-center retrospective analysis of metformin toxicity, what percentage of patients who did not meet EXTRIP criteria for ECTR died? 0% Trebach J, Mohan S, Gnirke M, Su MK, Gosselin S, Hoffman RS. Retrospective evaluation of management guidelines for extracorporeal treatment of metformin poisoning….

Historical QOD 11/24/08: What material is toxicologically unique in that it has the potential to act as both a chemical and a radiological toxicant? Depleted uranium (DU). DU has the capacity to cause renal injury as a chemical toxicant. Radiologically, DU emits alpha, beta and…

In a single-center retrospective analysis of metformin toxicity, what mortality beneft of ECTR was demonstrated in pateints who met criteria based on EXTRIP guidelines? There was no mortality benefit for dialysis in patients meeting EXTRIP criteria for ECTR Trebach J, Mohan S, Gnirke M, Su…

The below radiograph was obtained from an intentional rodenticide overdose. What was the ingested rodenticide? Zinc Phosphide. Haghighi-Morad M, Zamani N, Hassanian-Moghaddam H. Radiopaque rodenticide. Clin Toxicol (Phila). 2023 Feb 13:1-2. doi: 10.1080/15563650.2022.2163657. Epub ahead of print. PMID: 36779964.

In a recent retrospective review of Hymenoptera envenomation reported to the Taiwan National Poison Center, what differences were noted between Vespidae and Apidae? What were risk factors for severe outcomes? Calls for Vespidae enevenomation tended to be more severe than calls for Apidae. The factors…