Administrator Clintox - One

Following North American pit viper envenomation, what is the rate of delayed coagulopathy following treatment with Crotalidae immune F(ab’)2 versus Crotalidae polyvalent immune Fab? In a double-blind randomized clinical trial, the rate of delayed coagulopathy in patients treated with Crotalidae immune F(ab’)2 versus Crotalidae polyvalent…

Following bupropion overdose, what are clinical and electrocardiographic risk factors for adverse cardiovascular events defined as presence of ventricular arrhythmias, vasopressor use, myocardial injury, and/or cardiac arrest? In a recent retrospective analysis of data from the NPDA, risk factors associated with adverse cardiovascular events (defined…

For Agkistrodon contortrix (copperhead) envenomations, is there a difference between Fab AV (CroFab(r)) and F(ab’)2 AV (Anavip(r)) in the time or number of doses to achieve initial control of tissue injury effects? A randomized clinical trial compared both AVs in envenomations by North American pit…

Historical QOD 11/3/08: Acromelic acids are the probable etiologic agents of what disorder associated with consumption of mushrooms? Erythromelalgia from Clitocybe mushrooms Saviuc P, Danel V. New syndromes in mushroom poisoning. Toxicol Rev. 2006;25(3):199-209. doi: 10.2165/00139709-200625030-00004. PMID: 17192123.

What are the common symptoms of a black widow (Latrodectus) spider envenomation and the most common presenting symptom(s)? According to cited reference, “Symptoms of envenomation include diaphoresis, hypertension, muscle cramping, weakness, and pain either near or distant from the site of envenomation. The most common…

A black widow (Latrodectus) spider envenomation contains what primary toxin that leads to the release of what two primary neurotransmitters? According to the cited reference, “The primary toxin responsible for the envenomation syndrome in humans is α-latrotoxin. The neurotoxin binds to specific presynaptic receptors (neurexin…

According to a quantitative analysis of e-mails sent by predatory journals, what e-mail characteristics were associated with an increased odds ratio of being from a predatory journal versus non-predatory? Incorrect naming of the recipient (OR 8.10), “Greetings” in the e-mail (OR 28.60), Grammar mistakes (OR…

The FDA recently seized an imported weight-gain supplement, Apetamin. What ingredients does this drug contain and what toxidrome could occur in overdose? According to the cited reference, “Apetamin contains the prescription medication cyproheptadine, the amino acid lysine, and vitamins such as thiamine (vitamin B1) and…

Historical QOD 10/31/08: What is thought to be the composition of the chemical agent used by Russian Speznaz troops in the storming of the Moscow theater in which Chechyan rebels were holding hostages? A potent fentanyl derivative (such as carfentanil) and an inhalational anesthetic (possibly…