Administrator Clintox - One

Historical QOD 1/9/09: Which of the following would be an atypical presenting sign or symptom of Q fever? A: Fever B: Myalgias C: Hepatitis D: Cholecystitis E: Pneumonia d. The classic presentation is a flu-like illness with fevers, sweats, cough, myaglias, and arthralgias. Acute acalculous…

During a prospective, open labeled, three-way crossover trial that compared the efficacy and palatability of a charcoal cookie vs standard aqueous charcoal product in 2010, how much more palatable was the charcoal cookie was compared to the aqueous charcoal, if at all? The activated charcoal…

What are some factors which affect absorption in rectally administered aspirin? Formulation of aspirin, intestinal pH, and surface area all affect the rate of absorption of rectal aspirin. In absorption of aspirin, the rate limiting factor is particle dissolution. In more highly acidic environments, more…

A recent TikTok “body cleanse” challenge encourages viewers to ingest a cleaning substance that can result in a characteristic “boiled lobster” rash (see image). What is that substance? Sodium borate, boric acid, or Borax ingestion can lead to development of an intense generalized erythroderma with…

Venom of Heloderma suspectum, known as the Gila monster, can cause what rare but severe effect? Heloderma toxin contains gilatoxin, a serine protease with kallikrein activity, thought to be responsible for the hypotension and angioedema that has been reported in some human envenomations. Utaisincharoen P,…

Historical QOD 1/8/09: True or false:the use of alcohol containing mouthwash is associated with the development of oropharngeal cancer? False. While some have posited a causal association between the use of alcohol containing mouthwash and the development of oropharyngeal cancer over the past 25 years…

What was the “Zombie Outbreak” that occurred in 2016? According to the cited article, 18 people went to hospitals in Brooklyn, New York on July 12, 2016 for “zombie-like” activity. These individuals had altered mental status, lethargy, slow mechanical movements, and groaning. A comprehensive drug…

What is the mechanism of action for Yew plant cardiotoxicity? The yew plant (Taxus baccata) is a popular landscaping tree containing the toxic alkaloid taxine B. According to the cited article, taxine B exerts its cardiotoxic effects by inhibiting calcium and sodium channels on cardiac…

What active ingredient is found in black pepper extract and how does it affect the metabolism of other medications? According to the cited reference, piperine is the major constituent of black pepper extract, a popular dietary supplement advertised for its antioxidant properties and nutrient absorption…

What active ingredient is found in black pepper extract and how does it affect the metabolism of other medications? According to the cited reference, piperine is the major constituent of black pepper extract, a popular dietary supplement advertised for its antioxidant properties and nutrient absorption…