Administrator Clintox - One

Ingestion of what toxicant has been associated with feces and vomitus with a blue-green hue?   The signs and symptoms associated with boric acid ingestion are relatively non-specific and usually include nausea, vomiting and diarrhea. In addition to “boiled lobster” skin rash followed by desquamation,…

Ingestion of what toxicant has been associated with the development of so-called “boiled lobster” skin rash followed by desquamation within 48 hours?   Ingestion of boric acid has been associated with ‘boiled lobster’ rash and desquamation. Lung D et al. “Boiled lobster” rash of acute…

According to a recent MMWR report, during 2011-2015, there was an average of 93,296 alcohol-attributable deaths with 54.1% due to chronic conditions and 45.2% due to acute conditions. What was the leading acute cause of alcohol-attributal deaths?   Poisonings that involved another substance in addition…

What is the role of hemodialysis following acute baclofen overdose in a patient with normal kidney function?   In a recent case report published by Lee VR. et al, the amount of baclofen recovered during hemodialysis is negligible compared to the amount of baclofen cleared…

According to a recent review, adulteration is most common in what two classes of dietary supplements?   Supplements marketed for sexual enhancement and for weight loss are the two classes with the most reports of adulteration. (Drug Test Anal. 2020;12:861–886) This question was submitted on…

Elevated urine orotic acid is seen with several inborn errors of metabolism, including those of the urea cycle. Elevated urine orotic acid excretion may also be seen as a result of what drugs or supplements?   Allopurinol, by inhibiting pyrimidine synthesis, leads to increased urine…

Adulteration of an over the counter male enhancement product led to this severe complication, identified in 17 adults last year. What was the complication and what was the adulterant?   An OTC male enhancement product V8 was associated with hypoglycemia in 17 adults in Virginia…

Identify the above structure   The above structure is Tetrodotoxin, a potent sodium channel blocker. https://en.wikipedia.org/wiki/Tetrodotoxin

Identify the above structure   The above structure is Cantharidin. It is secreted by the blister beetle and sometimes touted as an aphrodesiac. https://en.wikipedia.org/wiki/Cantharidin

In a retrospective review of 79 pediatric and adolescent patient presenting with caustic ingestion from 1971-1983, what percentage of patients went on to develop esophageal stricture?   According to the cited referecence, the frequency of development of stricture in this group of patients was 4%….