Question of the Day – Wednesday December 30, 2020
Zolpidem has been shown to inhibit which channel that may lead to long QT syndrome and torsades de pointes? Human ether-a-go-go-related gene (hERG) Potassium Channels https://pubmed.ncbi.nlm.nih.gov/23061993/ Submitted by: Mary O’Keefe, PharmD on behalf of the Acute and Intensive Care Section
Question of the Day – Tuesday December 29, 2020
Exotic snakebites are relatively rare in the US and resulted in less than 1500 human exposure calls to poison centers over a 4 year time frame. This snake accounted for the greatest number of snakebite envenomations in 2 different studies. Monocled Cobra (Naja Kaouthia),…
Question of the Day – Monday December 28, 2020
In a recent study, what was one of the differences of F(AB’)-2 compared to FAB? a. Increased immediate allergic reactions in the F(AB’)-2 group b. Higher rate of type III hypersensitivity reactions in the F(AB’)-2 group compared to FAB group. c. Increased persistent, recurrent or…
Question of the Day – Wednesday December 23, 2020
Which fat substitute has been a suggested treatment for organochlorine toxicity? Olestra Redgrave TG, Wallace P, Jandacek RJ, Tso P. Treatment with a dietary fat substitute decreased Arochlor 1254 contamination in an obese diabetic male. J Nutr Biochem. 2005 Jun;16(6):383-4. doi: 10.1016/j.jnutbio.2004.12.014. PMID: 15936651….
Question of the Day – Tuesday December 22, 2020
What effect does N-acetylcysteine have on measurement of Prothrombin Time and what is a proposed mechanism? N-acetylcysteine has been shown in healthy volunteer subjects to interfere with PT measurement by decreasing the activity of factors II, VII, IX, and X. The mechanism is unclear,…
Question of the Day – Monday December 21, 2020
This biochemical marker has been theorized to be a predictor of delayed neurologic sequalae after carbon monoxide poisoning. Netrin-1. Netrin-1 has been previously investigated as a predictive biomarker of neurologic sequalae following both hemorrhagic and ischemic stroke. Kokulu K et al. sought to examine…
Question of the Day – Friday December 18, 2020
Aleurites Moluccana, often referred to as “Nuez de la India”, has been purported to be an effective weight loss supplement. Unfortunately, these non-toxic candlenuts have been mistaken for this which has resulted in toxicity? Due to similar appearances, candlenuts have been inadvertently substituted with…
AACT in the Military
Serving as an emergency physician and medical toxicologist in the United States Air Force in Afghanistan (2011) was an amazing experience. It was an honor for me to resuscitate patients, relieve pain and suffering, and provide the care my patients needed. While deployed I was…
Happy Holidays from AACT’s President
December 17, 2020 December is a month when many people around the world re-energize their spiritual lives and reconnect with family and friends. It is incredibly important to sustain emotional and mental wellness with so many external stressors like the pandemic and social injustice, and…
Question of the Day – Thursday December 17, 2020
In a recent randomized study in patients with anticholinergic toxicity, fewer patients that received physostigmine compared to lorazepam had this effect? Delirium. According to a recent paper by Wang et al., fewer patients receiving physostigmine had delirium compared to lorazepam. Wang GS et al….