In a 2019 pilot study on intranasal nalmefene as a rescue medication for synthetic opioid overdose, what dose of nalmefene with dodecyl maltoside (DDM) had a lower time to maximum concentration than intranasal naloxone?
3 mg of nalmefene with DDM
Krieter P, Gyaw S, Crystal R, Skolnick P. Fighting Fire with Fire: Development of Intranasal Nalmefene to Treat Synthetic Opioid Overdose. J Pharmacol Exp Ther. 2019;371(2):409-415. doi:10.1124/jpet.118.256115
Contributed by: Gabriela Gonzalez, PharmD Candidate on behalf of the Florida Poison Information Center Network
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